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SXSW Roll Call: Houston Here!

Published Mar 02, 2022 by David Ruiz

Houston on Skyline Screenshot

Houston innovation will make an appearance at this year’s South by Southwest (SXSW) Conference in Austin. For the second year in a row, the Greater Houston Partnership’s Houston House is preparing to showcase Houston leaders and companies accelerating the city’s thriving innovation ecosystem. From record-breaking venture capital activity to the energy transition, the Houston House line up will feature investors, startup founders and industry MVPs.

The Thrilling Tech Ecosystem 

Home to the largest medical center in the world, Houston’s innovation in life-sciences is a global commitment. This year’s lineup will unite leaders to discuss medical device technologies and the breakthroughs in cell behavior and medicine. The panels MedTech Transforming Healthcare Industry and Accelerating Innovation in Biotech will feature some of the industry’s top talent, highlighting local advancements in biotech reaching the global community.

The Bayou City’s competitive tech ecosystem continues to empower the region’s innovation activity and grow the esports sector. The electronic sports phenomenon has earned a spot in this year’s conference with the panel Game Changers: The Rise of Sports Tech. Panelists will dive into the explosive growth of esports, including the opportunities for founders, investors and fans. 

HOU to the Moon

Dubbed Space City, it’s clear Houston’s space exploration activity remains unrivaled on the national stage. The Houston House panel The Commercial Space Age Is Here will unite distinguished scientists from NASA and private space startups for an insightful discussion on how this cooperation is enabling the next frontier of space exploration.

Sustainable, Climate Resilient Houston

Following the Partnership’s release of the Houston Energy Transition Initiative, the region’s clean energy innovation has reached new limits and set higher goals. Houston’s ability to transition to clean energy while addressing climate change will continue to position it as a city of the future while remaining the Energy Capital of the World. 

This year’s lineup embraces Houston’s role in the global energy transition, powered by executives driving the solutions behind several of the world’s pressing issues. The panels Funding the Global Energy Transition, Dream Team: Corporates & Startups in ClimateTech, and Roadmap to an Equitable Energy Transition will bring together private and corporate investors to discuss the heightened importance of VC in the energy transition space, collaboration advancing low carbon solutions, regulatory deficiencies, and addressing economic inequities caused by climate change.

Innovation in energy transition will be the topic of discussion for the panel Tech Powering the Global Energy Transition. The Partnership’s own Senior Vice President of Energy Transition Jane Stricker will be joined by founders from some of the world's most promising energy tech startups to discuss their critical role in accelerating the global energy transition. 

Diversity in the Innovation Ecosystem

Despite being a critical force in the U.S. economy, diverse entrepreneurs represent a major funding gap. Access to funding remains a tightly guarded gateway to success and it breaks down to a trillion-dollar missed opportunity in the VC space. Houston House’s panel Funding the Next Generation of Diverse Founders will assemble leaders and investors to discuss the key challenges facing diverse entrepreneurs today and the necessary ingredients in building an inclusive innovation ecosystem.

Houston's participation at SXSW will culminate with a dynamic networking session hosted by HX Venture Fund Managing Director Sandy Guitar alongside Syzygy Plasmonics CEO Trevor Best. The networking event Meet Houston's Top Tech Founders will unite Houston's top founders, spotlighting innovation and discussing startup funding.

Houston House’s return to SXSW in person creates the ideal platform to promote Houston’s position as the most prominent emerging innovation hub in the country.

Learn more about Houston’s strengths and see our complete lineup online.

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Life Sciences

From Setback to Strategy: How San Jacinto College and Generation Park are Building Houston’s Biotech Workforce

4/28/25
Like every city, Houston experiences setbacks. The difference is Houston doesn’t dwell on them. It adapts, rebuilds and always comes back stronger. That’s exactly what the region is doing with biotech, an emerging sector where Houston is determined to lead.  The region’s economic development strategy shifted after losing Amazon’s HQ2 in 2019. Leaders doubled down on partnerships, long-term planning and industry diversification.  In 2022, there was another missed opportunity. A leading pharmaceutical company’s decision to choose North Carolina highlighted another critical gap in Houston – the need for a biotech workforce.   Rather than retreat, Houston responded with action. San Jacinto College (SJC) and Generation Park launched a bold partnership to build a biotech talent pipeline, ensuring the region is ready for the next big opportunity.  Learn more about Houston’s life sciences industry and how local colleges and businesses are working together to build the region’s biotech workforce.  SJC & Generation Park Partnership  Ryan McCord, McCord Development President and the visionary behind Generation Park, had long believed Houston could lead in life sciences. But as biotech investments flowed to other cities, it became clear: infrastructure alone wasn’t enough.  While Houston’s life sciences sector has grown steadily over the past decade— recording the second-highest employment growth rate among major markets from 2022 to 2023, according to CBRE’s 2025 Life Sciences Outlook—the region continued to face a shortage of technicians to support critical functions such as laboratory setup, data collection and research observation.  That’s when McCord turned to SJC, a proven leader in workforce development with a track record of building industry-aligned programs. Together, they launched the Center for Biotechnology, a workforce-first solution to close the talent gap and make Houston a top destination for biotech companies.  "San Jacinto College’s Biotechnology Center at Generation Park is the catalyst our region needs to fill the gap in our existing life science ecosystem and accelerate biomanufacturing in Houston,” said McCord in a news release.  Inside the Center for Biotechnology  Opening this summer, the Center for Biotechnology offers more than just textbook knowledge, it delivers hands-on training with industry-grade equipment. At its core is a pilot-scale bioprocessing plant where students will gain real-world experience using the same tools found in commercial facilities.   Click to expand To develop the curriculum, SJC partnered with the National Institute for Bioprocessing Research and Training (NIBRT), a global leader in biopharma education. That partnership makes the center the exclusive provider of NIBRT-licensed training in the southern U.S., and one of just six institutions worldwide with this distinction.  “Building on San Jacinto College’s established track record of working with industry to develop need-specific training and accreditation centers, the partnership with NIBRT represents an opportunity to train the workforce that Houston's biopharma industry needs to sustain its rapid growth,” said Brenda Hellyer, Chancellor of SJC, in a statement. “We also expect to contribute to the global market by training people eager to enter this growing industry from around the United States and beyond.”  The center also offers students exposure to emerging fields like cell and gene therapy. A regional advisory board of life sciences leaders will guide the curriculum to ensure it evolves with industry needs.  Strategic Location  The center is located within Generation Park, one of Houston’s fastest-growing innovation districts, and sits just steps away from BioHub Two, a 45-acre biomanufacturing campus currently under development. Once complete, BioHub Two will feature 500,000 square feet of state-of-the-art lab, office and cGMP manufacturing space, designed to attract life sciences companies to the region.   Click to expand What makes this proximity so powerful is the built-in connection between workforce development and industry growth. Companies moving into BioHub Two won’t just gain access to premier infrastructure, they’ll have a direct pipeline to trained, job-ready talent.  Spanning 4,300 acres, Generation Park is also home to leading institutions like Lone Star College and companies such as TechnipFMC and Apache Industrial Services. Beyond businesses, the district offers a great quality of life, surrounded by restaurants, shops, green space and residential options, all just a short drive from George Bush Intercontinental Airport and Port Houston.  Positioned for the Future  The partnership between SJC and Generation Park is more than a response to a missed opportunity – it’s a bold investment in Houston’s future. The Center for Biotechnology demonstrates how aligning education with industry needs can unlock long-term growth, strengthen the region’s talent pipeline, and position Houston as a national hub for life sciences innovation and biomanufacturing. 
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Life Sciences

Houston’s Biotech Ecosystem: The Ideal Launchpad for Life Sciences Startups

3/28/25
Launching a biotech startup is one of the most difficult undertakings in science and business. For Sarah Hein, founder and CEO of March Biosciences, choosing Houston made all the difference.  While most early-stage companies struggle to navigate the so-called "valleys of death" — the critical and often underfunded stages between research breakthroughs and real-world treatments — March Biosciences found the support it needed to move fast and scale its innovation. Hein credits Houston’s robust life sciences ecosystem for making that possible – saying Houston is one of the few places where you can go from the lab to commercialization.   “Houston has unique infrastructure and opportunities that made building March Bio here an obvious choice—the scientific and medical expertise of the largest medical center in the world, the local talent pool from that medical center, and then partnership opportunities,” Hein told the Greater Houston Partnership.  Want to learn more about Houston’s life sciences and biotech ecosystem, connect with the Partnership’s Global Life Sciences Sr. Director Verena Kallhoff.  From Research to a Life-Saving Therapy  March Bio was founded out of the Center for Cell and Gene Therapy (CAGT), a collaboration among Baylor College of Medicine (BCM), Houston Methodist and Texas Children’s Hospital. At the CAGT, March Bio worked with scientists to develop its lead therapy, MB-105, a CAR-T cell treatment targeting T-cell lymphoma and T-cell acute lymphoblastic leukemia, two aggressive cancers with limited treatment options.  CAR-T cell therapy involves collecting a patient’s own immune cells, engineering them to better recognize and attack cancer, and then reintroducing them into the body. Proximity to patients is essential for this personalized approach, and Houston’s concentration of clinical expertise makes it an ideal hub. As of mid-2024, the region hosted more than 2,200 active clinical trials, accounting for 11 percent of all trials in the U.S.  MB-105 showed a 44 percent patient response rate in Phase 1 trials at BCM. With that early success, March Bio turned to Houston’s ecosystem to accelerate its development.  Strategic Partnerships   In 2023, March Bio announced a strategic alliance with the CTMC, a joint effort between National Resilience and MD Anderson Cancer Center. CTMC provides biotech startups with comprehensive support, from development and manufacturing to regulatory guidance.   “Our close collaboration with MD Anderson Cancer Center provides access to leading regulatory expertise and one of the world's largest clinical trial programs, ensuring promising therapies reach patients faster,” Amy Hay, Chief Business Officer of CTMC, told the Partnership.  CTMC’s infrastructure enabled March Bio to grow without the financial burden of building its own facilities. “By taking on the heavy operational costs—housing the program in our 60,000 SF industrial-grade cGMP facility—CTMC enabled March to remain lean and focused on innovation,” she explained.   Fueling Growth Through Investment  Beyond research and partnerships, Houston offers the capital resources biotech companies need to grow, and March Biosciences has tapped into them at every stage of its journey.   The company secured early investment from the TMC Venture Fund and Portal Innovations, a venture capital firm that expanded to Houston in 2023 with the goal of supporting startups through funding, lab space and commercialization expertise.  “Portal’s investment in Houston is a mark of the growth and potential of the ecosystem,” said Hein. “March was their first biotech deal in Houston, and that early seed capital allowed us to get a lot of critical work done which set us up for our later financing success.”   March Bio’s momentum continued in 2024 with a $28.4 million Series A financing round, bringing its total amount raised to over $51 million.  Today, March Bio operates out of Portal’s labs at TMC Helix Park, where the company is currently conducting ongoing product development and early-stage discovery work.  State-level funding has been instrumental in fueling March Bio’s growth, with the Cancer Prevention and Research Institute of Texas (CPRIT) playing a significant role. March Bio was awarded a $13.4 million CPRIT grant to support its Phase 2 clinical trial. What sets CPRIT apart is that it is a state agency, established and funded by the State of Texas, making it one of the largest state-funded efforts against cancer. CPRIT has provided more than $3 billion in funding for cancer research and biotech innovation across Texas, contributing to a thriving life sciences ecosystem. With $6 billion dedicated to advancing cancer breakthroughs, CPRIT’s comprehensive approach supports the entire cancer care continuum while driving economic growth by attracting biotech companies and creating jobs. The company also received support from the Cancer Focus Fund, a MD Anderson–backed initiative that helps advance promising oncology therapies toward commercialization.  A Houston Success Story  Just four years after its founding in 2021, March Bio has advanced into Phase 2 trials and earned FDA orphan drug designation for MB-105. This designation is an important milestone that provides incentives such as tax credits and market exclusivity for rare disease treatments.  “Houston is home to the largest medical center in the world, with particular excellence in oncology, cardiovascular, and neurology research,” said Hein. “Patients come from all over the world to access the world class clinicians and novel clinical trials. Frankly, I think we simply have to keep doing the hard work of translating that leading research into the clinic, focusing on collaboration and growing our bench of talent, and the growth will follow.”  With its interconnected network of research institutions, capital resources, and strategic partners, Houston is proving to be a top destination for biotech companies. As the region continues investing in life sciences, more innovators like March Biosciences are expected to emerge, driving groundbreaking discoveries from concept to commercialization. 
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